A powerful anti-ageing serum for mature skin. Reduce wrinkles and fine lines with Duolys A.

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Multi-actions, this serum with 10 ingredients only and a silky texture acts on all the skin ageing. For people over the age of 30 years.

Turning back the signs of ageing thanks to the multi-action anti-ageing serum Duolys A. Containing only 10 ingredients, and with its unique and synergistic combination of Retinol and Tocopheryl retinoate, DUOLYS.A improves all the signs of ageing : wrinkles, lines, blemishes and skin texture, without ever irritating the skin and protecting it from the damage caused by oxidative stress.

Its exceptional galenic formula with its “oil-serum” texture is immediately absorbed into the skin with no sticky finish. Its ultra-light texture leaves skin feeling silky and velvety-soft. Your anti-ageing beauty routine is transformed into a moment of pure pleasure.

Day after day, skin appears firmer and complexion is more radiant Skin texture is refined. Wrinkles are less visible and skin imperfections are reduced.

98% ingredients of natural origin

Face – Neck – Neckline


Light and non-sticky “oil-serum” texture

Silky, soft and non-greasy finish

Non-comedogenic, non-acnegenic – No fragrance

Proven results







Tips and tricks

Apply a small amount of Duolys.A to the face, neck and neckline, preferably in the evening, to previously cleansed skin.

Avoid contact with eyes. For optimal results, use as a 3-month repeatable treatment. It can also be used in combination with Duolys.CE or as a follow-up treatment for cosmetic procedures.

If you experience a tingling sensation, apply less frequently. Not for use by pregnant women or those planning a pregnancy. Limit sun exposure and apply an appropriate sun protective product. Keep the product at a temperature below 25°C.

Anti-ageing efficacy proven in studies

Over 90% of women would like to continue using the product (1,b)

Very good skin tolerance


1.Evaluation of the cutaneous acceptability and comedogenic potential of Duolys.A, conducted under dermatological control on 22 adult women over 28 days aged between 20 and 47 years old

a. Tolerance

No clinical signs of intolerance were observed and no functional or physical signs were reported by volunteers at D28.

The product demonstrates very good skin tolerance.

b. Patient evaluation

Users responded very positively to Duolys.A: over 90% of women would like to continue using the product.

- 100%* find the texture pleasant and non-sticky with a silky finish

- 100%* say their skin is smoother

- 100%* have softer, deeply-moisturised skin

- 95%* find that skin texture is refined

- 82%* say skin appears younger

- 87%* find that the product reduces skin imperfections

- 85%* : Rides moins visibles (constaté sur 13 volontaires)

*% of satisfaction

2. Anti-ageing efficacy proven in studies on human (ex vivo)

  • Significant increase (20 to 30%) in collagen i from day 4 and iii synthesis in the dermis from day 9
  • 10% significant increase in epidermal thickness from day
  • Excellent skin tolerance - In contrast to the results usually obtained with vitamin A-based products (retinol, retinaldehyde, retinoic acid), which generally cause inflammation and a decrease in cell viability, Duolys.A Intensive Anti-Wrinkle Serum offers optimal skin tolerance and does not affect cell viability.

A combination of Retinol and Tocopheryl retinoate with optimal tolerance

Minimalist formula with just 10 essential ingredients

Caprylic/Capric Triglyceride, Castor Oil/IPDI Copolymer, Coco-Caprylate/Caprate, Dicaprylyl Carbonate, Glycine Soja (Soybean) Oil, Helianthus Annuus (Sunflower) Seed Oil, Hydrogenated Coconut Acid, Retinol, Tocopherol, Tocopheryl Retinoate